Paclitaxel FDA Link Generic

A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.

Also Known As:

Taxol; Anzatax; Paxene; 7-epi-Taxol; Bris Taxol; NSC-125973; Onxol; Paclitaxel, (4 alpha)-Isomer; Praxel; Taxol A; 7 epi Taxol; NSC 125973; NSC125973; Taxol, Bris; Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12b- bis(acetyloxy)- 12- (benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b- dodecahydro- 4,11- dihydroxy- 4a,8,13,13- tetramethyl- 5- oxo- 7,11- methano- 1H- cyclodeca(3,4)benz(1,2- b)oxet- 9- yl ester, (2aR- (2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,1- 2alpha,12aalpha,12balpha))-

Pharmalogical Action Categories:

Antineoplastic Agents, Phytogenic
Tubulin Modulators

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - Taxoids: 2650
        Paclitaxel: 22016
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cyclodecanes
        Taxoids: 2650
        Paclitaxel: 22016

K James Bilof Selected Research

K James Bilof Research Topics

Disease

Drug/Important Bio-Agent (IBA)